BDBM50336958 2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thiopheno[3,2-d]pyrimidin-6-one::CHEMBL1672575

SMILES COc1ncc2sc3c(SCCNC3=O)c2n1

InChI Key InChIKey=FTCSRLCKGZJDCK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50336958   

TargetSerine/threonine-protein kinase D1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50336958(2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thioph...)
Affinity DataIC50: 124nMAssay Description:Inhibition of human recombinant PKD1 after 10 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50336958(2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thioph...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPolycystin-2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50336958(2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thioph...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant PKD2 after 10 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed