BDBM50336951 1-((4-(5-(2,4-Difluorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid::CHEMBL1672561

SMILES OC(=O)C1CN(Cc2ccc(-c3nc4cc(Cc5ccc(F)cc5F)ccc4s3)c(F)c2)C1

InChI Key InChIKey=OTMDEGQUSPOEAC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336951   

TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336951(1-((4-(5-(2,4-Difluorobenzyl)benzo[d]thiazol-2-yl)...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO-K1 cells co-expressing Gq/i5 G-protein assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336951(1-((4-(5-(2,4-Difluorobenzyl)benzo[d]thiazol-2-yl)...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed