BDBM50336936 CHEMBL1672543::N-(3-(4-cyanophenyl)-1-methyl-1H-indol-6-yl)methanesulfonamide

SMILES Cn1cc(-c2ccc(cc2)C#N)c2ccc(NS(C)(=O)=O)cc12

InChI Key InChIKey=CHKQRCNHKANTSK-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50336936   

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336936(N-(3-(4-cyanophenyl)-1-methyl-1H-indol-6-yl)methan...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336936(N-(3-(4-cyanophenyl)-1-methyl-1H-indol-6-yl)methan...)
Affinity DataIC50: 485nMAssay Description:Antagonist activity at human progesterone receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by GRE-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336936(N-(3-(4-cyanophenyl)-1-methyl-1H-indol-6-yl)methan...)
Affinity DataKi: >4.02E+3nMAssay Description:Displacement of [3H]methyltrienolone from human androgen receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336936(N-(3-(4-cyanophenyl)-1-methyl-1H-indol-6-yl)methan...)
Affinity DataKi: >4.17E+3nMAssay Description:Displacement of [3H]methyltrienolone from human mineralocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336936(N-(3-(4-cyanophenyl)-1-methyl-1H-indol-6-yl)methan...)
Affinity DataKi: >4.29E+3nMAssay Description:Displacement of [3H]methyltrienolone from human glucocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336936(N-(3-(4-cyanophenyl)-1-methyl-1H-indol-6-yl)methan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed