BDBM50336929 (R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl)methanesulfonamide::CHEMBL1672549

SMILES CC[C@@H](C)n1cc(-c2ccc(cc2)C#N)c2ccc(NS(C)(=O)=O)cc12

InChI Key InChIKey=QFRVNOIAPBNRJM-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50336929   

TargetMineralocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336929((R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336929((R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl...)
Affinity DataIC50: 9.92nMAssay Description:Antagonist activity at human progesterone receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by GRE-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336929((R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl...)
Affinity DataKi:  0.834nMAssay Description:Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336929((R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl...)
Affinity DataKi:  780nMAssay Description:Displacement of [3H]methyltrienolone from human glucocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336929((R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]methyltrienolone from human mineralocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336929((R)-N-(1-sec-butyl-3-(4-cyanophenyl)-1H-indol-6-yl...)
Affinity DataKi:  2.55E+3nMAssay Description:Displacement of [3H]methyltrienolone from human androgen receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed