BDBM50336817 5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methylphenyl)-2-(2-methylpropyl)pyridine-3-carboxylic Acid Dihydrochloride::CHEMBL1672124

SMILES CC(C)Cc1nc(CC(C)(C)C)c(CN)c(-c2ccc(C)cc2)c1C(O)=O

InChI Key InChIKey=WBWMMMGDTXEGFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336817   

TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336817(5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methyl...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of DPP4 in human Caco2 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336817(5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat kidney DPP2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336817(5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methyl...)
Affinity DataIC50: 420nMAssay Description:Inhibition of FLAG-tagged human DPP8 expressed in human 293F cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50336817(5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FLAG-tagged human DPP9 expressed in human 293F cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed