BDBM50336392 (S)-4-(2-(2-(4-chlorophenyl)-5-fluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)-3-fluorobenzoic acid::CHEMBL1668258

SMILES OC(=O)c1ccc(NC(=O)[C@H](C2CCCCC2)n2c(nc3cc(F)ccc23)-c2ccc(Cl)cc2)c(F)c1

InChI Key InChIKey=ZEZBGNHZVYOPGB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336392   

TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336392((S)-4-(2-(2-(4-chlorophenyl)-5-fluoro-1H-benzo[d]i...)
Affinity DataIC50: 40nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetBile acid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336392((S)-4-(2-(2-(4-chlorophenyl)-5-fluoro-1H-benzo[d]i...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at Gal4-fused human FXR by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed