BDBM50336161 CHEMBL1669549::N-cyclopentyl-4-fluoro-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxamide

SMILES Fc1c(noc1-c1ccc(cc1)C(F)(F)F)C(=O)NC1CCCC1

InChI Key InChIKey=MRRGWDHQTLHWIH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336161   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharpe and Dohme

Curated by ChEMBL

LigandBDBM50336161(N-cyclopentyl-4-fluoro-5-(4-(trifluoromethyl)pheny...)Copy SMILESCopy InChI

Affinity DataIC50: 112nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
Entry Details Article
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