BDBM50336159 4-bromo-N-cyclopentyl-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxamide::CHEMBL1669547

SMILES FC(F)(F)c1ccc(cc1)-c1onc(C(=O)NC2CCCC2)c1Br

InChI Key InChIKey=YVNWJVBYLAVLEP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336159   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharpe and Dohme

Curated by ChEMBL

LigandBDBM50336159(4-bromo-N-cyclopentyl-5-(4-(trifluoromethyl)phenyl...)Copy SMILESCopy InChI

Affinity DataIC50: 46nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
Entry Details Article
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