BDBM50336153 (4-chloro-5-(4-(trifluoromethyl)phenyl)isoxazol-3-yl)(4-hydroxypiperidin-1-yl)methanone::CHEMBL1669522

SMILES OC1CCN(CC1)C(=O)c1noc(c1Cl)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=CZUCFJFFPOZNMO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336153   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharpe and Dohme

Curated by ChEMBL

LigandBDBM50336153((4-chloro-5-(4-(trifluoromethyl)phenyl)isoxazol-3-...)Copy SMILESCopy InChI

Affinity DataIC50: 263nMAssay Description:Agonist activity at human TRPV1 expressed in CHO cells assessed as capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
Entry Details Article
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