BDBM50336151 (1R,3S)-4-chloro-5-(4-fluorophenyl)-N-(3-hydroxycyclohexyl)isoxazole-3-carboxamide::CHEMBL1669539

SMILES O[C@H]1CCC[C@H](C1)NC(=O)c1noc(c1Cl)-c1ccc(F)cc1

InChI Key InChIKey=DQLAUWNFVBOPJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336151   

LigandPNGBDBM50336151((1R,3S)-4-chloro-5-(4-fluorophenyl)-N-(3-hydroxycy...)
Affinity DataIC50: 141nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336151((1R,3S)-4-chloro-5-(4-fluorophenyl)-N-(3-hydroxycy...)
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed