BDBM50336148 4-chloro-N-(3-hydroxyphenyl)-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxamide::CHEMBL1669536

SMILES Oc1cccc(NC(=O)c2noc(c2Cl)-c2ccc(cc2)C(F)(F)F)c1

InChI Key InChIKey=GKCADXGQKUQVGX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336148   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharpe and Dohme

Curated by ChEMBL

LigandBDBM50336148(4-chloro-N-(3-hydroxyphenyl)-5-(4-(trifluoromethyl...)Copy SMILESCopy InChI

Affinity DataIC50: 118nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
Entry Details Article
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