BDBM50336137 CHEMBL1669526::Trans-4-chloro-N-((1r,4r)-4-hydroxycyclohexyl)-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxamide

SMILES O[C@H]1CC[C@@H](CC1)NC(=O)c1noc(c1Cl)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=XHNHZYYEGAEZLU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336137   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharpe and Dohme

Curated by ChEMBL

LigandBDBM50336137(Trans-4-chloro-N-((1r,4r)-4-hydroxycyclohexyl)-5-(...)Copy SMILESCopy InChI

Affinity DataIC50: 392nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
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