BDBM50336136 4-chloro-N-(tetrahydro-2H-pyran-4-yl)-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxamide::CHEMBL1669525

SMILES FC(F)(F)c1ccc(cc1)-c1onc(C(=O)NC2CCOCC2)c1Cl

InChI Key InChIKey=LIDGBRAZRUHROL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336136   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharpe and Dohme

Curated by ChEMBL

LigandBDBM50336136(4-chloro-N-(tetrahydro-2H-pyran-4-yl)-5-(4-(triflu...)Copy SMILESCopy InChI

Affinity DataIC50: 43nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
Entry Details Article
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