BDBM50336023 CHEMBL4162351

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)NC1(CCc2ccccc2C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O

InChI Key InChIKey=KZXPBIGXGGBZGL-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336023   

TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50336023(CHEMBL4162351)
Affinity DataIC50: 8.80nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50336023(CHEMBL4162351)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR2 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50336023(CHEMBL4162351)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human NMUR1 expressed in HEK293 cells assessed as IP3 accumulation after 60 mins in presence of myo-[2-3H(N)]inositol by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50336023(CHEMBL4162351)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at human NMUR2 expressed in HEK293 cells assessed as IP3 accumulation after 60 mins in presence of myo-[2-3H(N)]inositol by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed