BDBM50335972 1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea::CHEMBL1668932

SMILES CC(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WGDIJYGQSIUZOV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335972   

TargetBifunctional epoxide hydrolase 2(Human)
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335972(1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)p...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335972(1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)p...)
Affinity DataIC50: 98nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335972(1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)p...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed