BDBM50335820 6-(3-Hydroxyphenyl)-1-(pyridin-4-yl)-2-naphthol::CHEMBL1650647::US8546392, 52::US8546392, 68

SMILES Oc1cccc(c1)-c1ccc2c(c(O)ccc2c1)-c1ccncc1

InChI Key InChIKey=LQVXBXGVWKFEJF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335820   

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335820(CHEMBL1650647 | US8546392, 68 | US8546392, 52 | 6-...)
Affinity DataIC50: 39nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2013
Entry Details
Go to US Patent

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335820(CHEMBL1650647 | US8546392, 68 | US8546392, 52 | 6-...)
Affinity DataIC50: 583nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2013
Entry Details
Go to US Patent

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335820(CHEMBL1650647 | US8546392, 68 | US8546392, 52 | 6-...)
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]E1 from human placental 17beta-HSD1 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335820(CHEMBL1650647 | US8546392, 68 | US8546392, 52 | 6-...)
Affinity DataIC50: 3.34E+3nMAssay Description:Displacement of [3H]E2 from human placental 17beta-HSD2 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed