BDBM50335682 (S)-4-fluoro-2-(6-methoxy-7-(2-methoxyethoxy)-4-(pyrrolidin-3-ylamino)quinazolin-2-yl)phenol::CHEMBL1650127

SMILES COCCOc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1cc(F)ccc1O

InChI Key InChIKey=YGSLRVBZRCPLON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335682   

TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335682((S)-4-fluoro-2-(6-methoxy-7-(2-methoxyethoxy)-4-(p...)
Affinity DataIC50: 260nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335682((S)-4-fluoro-2-(6-methoxy-7-(2-methoxyethoxy)-4-(p...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed