BDBM50335610 3-((4-(6-chloro-2-(4-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole::CHEMBL1651456

SMILES CN1CCN(CC1)c1ccc(cc1)-c1nc2ncc(Cl)c(N3CCN(Cc4cc(C)on4)CC3)c2[nH]1

InChI Key InChIKey=DRNKFZMXQOCVNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335610   

TargetAurora kinase A(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50335610(3-((4-(6-chloro-2-(4-(4-methylpiperazin-1-yl)pheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335610(3-((4-(6-chloro-2-(4-(4-methylpiperazin-1-yl)pheny...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ERG by whole-cell voltage clampingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed