BDBM50335405 2-(2-(cyclohexanecarboxamido)-6-morpholino-9H-purin-9-yl)acetic acid::CHEMBL1651691

SMILES OC(=O)Cn1cnc2c(nc(NC(=O)C3CCCCC3)nc12)N1CCOCC1

InChI Key InChIKey=YFCASXKFFIBHBP-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335405   

LigandPNGBDBM50335405(2-(2-(cyclohexanecarboxamido)-6-morpholino-9H-puri...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to mouse Stat3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50335405(2-(2-(cyclohexanecarboxamido)-6-morpholino-9H-puri...)
Affinity DataIC50: 6.44E+4nMAssay Description:Inhibition of mouse Stat3 DNA binding activity by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50335405(2-(2-(cyclohexanecarboxamido)-6-morpholino-9H-puri...)
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of STAT3 phosphorylation at Tyr705 residue in human MDA-MB-231 cells by sandwich-ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed