BDBM50335339 2-(4-tert-Butylphenyl)-4-(5-methyl-1H-pyrazol-3-ylamino)-2H-phthalazin-1-one::CHEMBL1651472

SMILES Cc1cc(Nc2nn(-c3ccc(cc3)C(C)(C)C)c(=O)c3ccccc23)[nH]n1

InChI Key InChIKey=AIHXCSFEMCZERD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335339   

TargetAurora kinase B(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50335339(2-(4-tert-Butylphenyl)-4-(5-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Aurora B by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50335339(2-(4-tert-Butylphenyl)-4-(5-methyl-1H-pyrazol-3-yl...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed