BDBM50335290 CHEMBL1651362::N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-N-methylleucyl-methylazalanine-nitrile::acs.jmedchem.1c00409_ST.410

SMILES CC(C)C[C@H](N(C)C(=O)c1ccc(cc1)-c1noc(n1)-c1cccs1)C(=O)N(C)N(C)C#N

InChI Key InChIKey=VQKRNTTUZDCHOZ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335290   

TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50335290(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-...)
Affinity DataIC50: 5.54E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetCathepsin K(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335290(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-...)
Affinity DataKi:  0.630nMAssay Description:Inhibition of human recombinant cathepsin K after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335290(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-...)
Affinity DataKi:  140nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335290(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-...)
Affinity DataKi:  510nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335290(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed