BDBM50335285 CHEMBL1651350::N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcarbamoyl}-leucyl-methylazalanine-nitrile::acs.jmedchem.1c00409_ST.407

SMILES CC(C)C[C@H](NC(=O)Nc1ccc(cc1)-c1noc(n1)-c1cccs1)C(=O)N(C)N(C)C#N

InChI Key InChIKey=KFTMZNIURYIOKI-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335285   

TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50335285(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcar...)
Affinity DataIC50: 3.99E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetCathepsin K(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335285(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcar...)
Affinity DataKi:  0.0220nMAssay Description:Inhibition of human recombinant cathepsin K after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335285(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcar...)
Affinity DataKi:  0.320nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335285(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcar...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335285(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcar...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed