BDBM50335282 CHEMBL1651356::N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzylcarbamoyl]-leucyl-methylazaalanine-nitrile::acs.jmedchem.1c00409_ST.405

SMILES CC(C)C[C@H](NC(=O)NCc1ccc(cc1)-c1noc(C)n1)C(=O)N(C)N(C)C#N

InChI Key InChIKey=LRGPAVMYPWWORG-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335282   

TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50335282(N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzylcarbamoy...)
Affinity DataIC50: 2.55E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetCathepsin K(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335282(N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzylcarbamoy...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of human recombinant cathepsin K after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335282(N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzylcarbamoy...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335282(N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzylcarbamoy...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335282(N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzylcarbamoy...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed