BDBM50335225 (S)-1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid 3-(3,4,5-trimethoxy-phenyl)-propyl ester::(S)-3-(3,4,5-Trimethoxyphenyl)propyl 1-(benzylsulfonyl)-piperidine-2-carboxylate::CHEMBL109278

SMILES COc1cc(cc(c1OC)OC)CCCOC(=O)[C@@H]2CCCCN2S(=O)(=O)Cc3ccccc3

InChI Key InChIKey=WUVVOAPMLQTLBJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335225   

TargetOuter membrane protein MIP(Legionella pneumophila)
University of Wu£Rzburg

Curated by ChEMBL
LigandPNGBDBM50335225((S)-1-Phenylmethanesulfonyl-piperidine-2-carboxyli...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of PPIase activity of Legionella pneumophila MIP protein expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
University of Wu£Rzburg

Curated by ChEMBL
LigandPNGBDBM50335225((S)-1-Phenylmethanesulfonyl-piperidine-2-carboxyli...)
Affinity DataIC50: 200nMAssay Description:Inhibition of PPIase activity of human FKBP12 expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
University of Wu£Rzburg

Curated by ChEMBL
LigandPNGBDBM50335225((S)-1-Phenylmethanesulfonyl-piperidine-2-carboxyli...)
Affinity DataKi:  230nMAssay Description:Inhibition of FKBP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
University of Wu£Rzburg

Curated by ChEMBL
LigandPNGBDBM50335225((S)-1-Phenylmethanesulfonyl-piperidine-2-carboxyli...)
Affinity DataKi:  230nMAssay Description:Inhibition of recombinant human FKBP12 expressed in Escherichia coli using succinyl-Ala-Phe-Pro-Phe-4-nitroanilide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed