BDBM50335175 3-[7-Chloro-5-(2-trifluoromethyl-phenyl)-1H-benzimidazol-2-yl]-1,8-dioxa-2-aza-spiro[4.5]dec-2-ene::CHEMBL1650532

SMILES FC(F)(F)c1ccccc1-c1cc(Cl)c2[nH]c(nc2c1)C1=NOC2(C1)CCOCC2

InChI Key InChIKey=HLMKJRBWLAKJSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335175   

TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50335175(3-[7-Chloro-5-(2-trifluoromethyl-phenyl)-1H-benzim...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at canine TRPM8 expressed in HEK293 cells assessed as inhibition of intracellular calcium accumulation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed