BDBM50334972 CHEMBL1649912::endo-4,4-difluoro-N-((S)-3-(3-(5-isopropyl-3-methyl-1H-1,2,4-triazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)cyclohexanecarboxamide

SMILES CC(C)c1nc(C)nn1[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334972   

LigandPNGBDBM50334972(endo-4,4-difluoro-N-((S)-3-(3-(5-isopropyl-3-methy...)
Affinity DataIC50: 4.23E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334972(endo-4,4-difluoro-N-((S)-3-(3-(5-isopropyl-3-methy...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed