BDBM50334929 1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c]pyrazol-1(4H)-yl]phenyl}methyl)-2-pyrrolidinone::CHEMBL1649681

SMILES c1cc(ccc1CN2CCCC2=O)n3c4c(c(n3)C(F)(F)F)COCC4

InChI Key InChIKey=URIDIEFPWLZYEF-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50334929   

TargetCytochrome P450 2C19(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed