BDBM50334828 CHEMBL1643160::N-(4-(5-cyano-7-methylbenzo[d]oxazol-2-yl)phenyl)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamide

SMILES Cc1cc(cc2nc(oc12)-c1ccc(NC(=O)CN2CCN(CC2)c2cccc(c2)C(F)(F)F)cc1)C#N

InChI Key InChIKey=TWXKMLUDQFBGTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334828   

TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334828(N-(4-(5-cyano-7-methylbenzo[d]oxazol-2-yl)phenyl)-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant CETP-mediated cholesteryl ester transfer by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334828(N-(4-(5-cyano-7-methylbenzo[d]oxazol-2-yl)phenyl)-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant CETP-mediated triglyceride transfer by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed