BDBM50334781 CHEMBL1642912::Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-2-yl)ethanamine

SMILES NCC[C@H]1C[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1

InChI Key InChIKey=SNDGNPRZZZPUAX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50334781   

TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 265nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed