BDBM50334772 CHEMBL1642903::cis-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-2-yl)methanamine

SMILES NC[C@@H]1C[C@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1

InChI Key InChIKey=AUOZLNRXVPELRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334772   

TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334772(cis-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334772(cis-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 257nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334772(cis-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 111nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed