BDBM50334771 CHEMBL1642901::cis-(2R,4R)-4-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine

SMILES CN(C)[C@@H]1C[C@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1

InChI Key InChIKey=DVCQRBZBVYAGNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334771   

TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334771(cis-(2R,4R)-4-(3,4-dichlorophenyl)-N,N-dimethyl-1,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334771(cis-(2R,4R)-4-(3,4-dichlorophenyl)-N,N-dimethyl-1,...)
Affinity DataIC50: 98nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334771(cis-(2R,4R)-4-(3,4-dichlorophenyl)-N,N-dimethyl-1,...)
Affinity DataIC50: 319nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed