BDBM50334746 CHEMBL1642848::N1-3-(Napthalene-1-sulfonyl-1H-indazol-5-yl)-ethane-1,2-diamine HCl

SMILES NCCNc1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=RQOKMHCTFHXXMM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334746   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334746(N1-3-(Napthalene-1-sulfonyl-1H-indazol-5-yl)-ethan...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334746(N1-3-(Napthalene-1-sulfonyl-1H-indazol-5-yl)-ethan...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed