BDBM50334729 CHEMBL1642863::N,N,N'-Trimethyl-N0-{[3-(1-naphthylsulfonyl)-1H-indazol-5-yl]methyl}ethane-1,2-diamine HCl

SMILES CN(C)CCN(C)Cc1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=YVZYTWQZGQNPAY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334729   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334729(N,N,N'-Trimethyl-N0-{[3-(1-naphthylsulfonyl)-1H-in...)
Affinity DataIC50: 91nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334729(N,N,N'-Trimethyl-N0-{[3-(1-naphthylsulfonyl)-1H-in...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed