BDBM50334718 3-(Naphthalen-1-ylsulfonyl)-N-(piperidin-4-ylmethyl)-1Hindazol-5-amine HCl::CHEMBL1642853

SMILES O=S(=O)(c1n[nH]c2ccc(NCC3CCNCC3)cc12)c1cccc2ccccc12

InChI Key InChIKey=UZICKKVMOVQUOD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334718   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334718(3-(Naphthalen-1-ylsulfonyl)-N-(piperidin-4-ylmethy...)
Affinity DataIC50: 174nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334718(3-(Naphthalen-1-ylsulfonyl)-N-(piperidin-4-ylmethy...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed