BDBM50334403 5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]inden-10-yl)-azetidin-3-yloxy]-1,3-dihydro-indol-2-one::CHEMBL1643859

SMILES O=C1Cc2cc(OC3CN(C3)c3c4CCNCCc4nc4ccnn34)ccc2N1

InChI Key InChIKey=BLAATJSMNSTOKH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334403   

Target5-hydroxytryptamine receptor 2C(Human)
Evotec

Curated by ChEMBL
LigandPNGBDBM50334403(5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyc...)
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Evotec

Curated by ChEMBL
LigandPNGBDBM50334403(5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyc...)
Affinity DataEC50:  762nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Evotec

Curated by ChEMBL
LigandPNGBDBM50334403(5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyc...)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed