BDBM50334368 CHEMBL1643325::N-(2-aminophenyl)-3-(4-(2-(4'-cyclopropylbiphenyl-4-ylamino)-2-oxo-1-(2-(piperidin-1-yl)ethylamino)ethyl)phenyl)acrylamide

SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(cc1)C(NCCN1CCCCC1)C(=O)Nc1ccc(cc1)C1CC1

InChI Key InChIKey=JFMYZNIWQJZXIC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334368   

TargetHistone deacetylase 1(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334368(N-(2-aminophenyl)-3-(4-(2-(4'-cyclopropylbiphenyl-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334368(N-(2-aminophenyl)-3-(4-(2-(4'-cyclopropylbiphenyl-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334368(N-(2-aminophenyl)-3-(4-(2-(4'-cyclopropylbiphenyl-...)
Affinity DataIC50: 360nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed