BDBM50334367 CHEMBL1643315::N-(2-aminophenyl)-3-(4-(2-oxo-1-(2-(tetrahydro-2H-pyran-4-yl)ethylamino)-2-(4-(trifluoromethyl)phenylamino)ethyl)phenyl)acrylamide

SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(cc1)C(NCCC1CCOCC1)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=PYXSQEBHAOBWDL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334367   

TargetHistone deacetylase 1(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334367(N-(2-aminophenyl)-3-(4-(2-oxo-1-(2-(tetrahydro-2H-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334367(N-(2-aminophenyl)-3-(4-(2-oxo-1-(2-(tetrahydro-2H-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50334367(N-(2-aminophenyl)-3-(4-(2-oxo-1-(2-(tetrahydro-2H-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed