BDBM50334271 6-(methylthio)-9H-purin-2-amine::6-methylsulfanyl-7H-purin-2-amine::CHEMBL1172777

SMILES CSc1nc(N)nc2nc[nH]c12

InChI Key InChIKey=YEGKYFQLKYGHAR-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334271   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50334271(6-(methylthio)-9H-purin-2-amine | 6-methylsulfanyl...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of ASK1 assessed as phosphorylated fluorescent peptide by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pontifical Catholic University of Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50334271(6-(methylthio)-9H-purin-2-amine | 6-methylsulfanyl...)
Affinity DataKd:  3.16E+5nMAssay Description:Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed