BDBM50334153 CHEMBL1645164::methyl 2-((4-(3-(4-bromophenyl)-3-(4-fluorophenyl)propanoyl)piperazin-1-yl)methyl)oxazole-4-carboxylate

SMILES COC(=O)c1coc(CN2CCN(CC2)C(=O)CC(c2ccc(F)cc2)c2ccc(Br)cc2)n1

InChI Key InChIKey=ZDYQLRISEQXUFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334153   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50334153(methyl 2-((4-(3-(4-bromophenyl)-3-(4-fluorophenyl)...)
Affinity DataIC50: 860nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50334153(methyl 2-((4-(3-(4-bromophenyl)-3-(4-fluorophenyl)...)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed