BDBM50334094 3-chloro-2-(5-chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)pyrimidin-4-ylamino)-N-methylbenzamide::CHEMBL1644806

SMILES CNC(=O)c1cccc(Cl)c1Nc1nc(Nc2ccc3NC(=O)CCC(C)(C)c3c2)ncc1Cl

InChI Key InChIKey=CXVYNVKRAHOLMU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334094   

TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334094(3-chloro-2-(5-chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5...)
Affinity DataIC50: 159nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334094(3-chloro-2-(5-chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human c-Met in human GTL16 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334094(3-chloro-2-(5-chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of IR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed