BDBM50334092 2-(5-chloro-2-(1-ethyl-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)pyrimidin-4-ylamino)-3-fluoro-N-methylbenzamide::CHEMBL1644808

SMILES CCN1c2ccc(Nc3ncc(Cl)c(Nc4c(F)cccc4C(=O)NC)n3)cc2C(C)(C)CCC1=O

InChI Key InChIKey=MIXZFFBSISECDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334092   

TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334092(2-(5-chloro-2-(1-ethyl-5,5-dimethyl-2-oxo-2,3,4,5-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334092(2-(5-chloro-2-(1-ethyl-5,5-dimethyl-2-oxo-2,3,4,5-...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human c-Met in human GTL16 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334092(2-(5-chloro-2-(1-ethyl-5,5-dimethyl-2-oxo-2,3,4,5-...)
Affinity DataIC50: 334nMAssay Description:Inhibition of IR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed