BDBM50334082 2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-N-prop-2-ynyl-benzamide::CHEMBL1644802

SMILES CN1c2ccc(Nc3ncc(Cl)c(Nc4ccccc4C(=O)NCC#C)n3)cc2CCCC1=O

InChI Key InChIKey=AWKVKBJHESFTRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334082   

TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334082(2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1...)
Affinity DataIC50: 8nMAssay Description:Inhibition of IR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334082(2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1...)
Affinity DataIC50: 17nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334082(2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human c-Met in human GTL16 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed