BDBM50333964 CHEMBL1644481::exo-(1R,5S)-3-(3-(trifluoromethyl)phenoxy)-8-azabicyclo[3.2.1]octane

SMILES FC(F)(F)c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1

InChI Key InChIKey=CIJDXZHBTVURGN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333964   

LigandPNGBDBM50333964(exo-(1R,5S)-3-(3-(trifluoromethyl)phenoxy)-8-azabi...)
Affinity DataIC50: 128nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333964(exo-(1R,5S)-3-(3-(trifluoromethyl)phenoxy)-8-azabi...)
Affinity DataIC50: 99nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333964(exo-(1R,5S)-3-(3-(trifluoromethyl)phenoxy)-8-azabi...)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed