BDBM50333962 CHEMBL1644479::exo-(1R,5S)-3-(m-tolyloxy)-8-azabicyclo[3.2.1]octane

SMILES Cc1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1

InChI Key InChIKey=PHOVKMVBVOKTKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333962   

LigandPNGBDBM50333962(exo-(1R,5S)-3-(m-tolyloxy)-8-azabicyclo[3.2.1]octa...)
Affinity DataIC50: 92nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333962(exo-(1R,5S)-3-(m-tolyloxy)-8-azabicyclo[3.2.1]octa...)
Affinity DataIC50: 624nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333962(exo-(1R,5S)-3-(m-tolyloxy)-8-azabicyclo[3.2.1]octa...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed