BDBM50333936 CHEMBL1644425::trans-4-((5-(4-(trifluoromethoxy)phenyl)isothiazole-3-carboxamido)methyl)cyclohexanecarboxylic acid

SMILES OC(=O)[C@H]1CC[C@H](CNC(=O)c2cc(sn2)-c2ccc(OC(F)(F)F)cc2)CC1

InChI Key InChIKey=JDXMRLUMLAYKFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333936   

TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333936(trans-4-((5-(4-(trifluoromethoxy)phenyl)isothiazol...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed