BDBM50333820 3-(6-Morpholino-2-(2-(pyridin-2-yl)ethylamino)pyrimidin-4-yl)phenol::CHEMBL1644571

SMILES Oc1cccc(c1)-c1cc(nc(NCCc2ccccn2)n1)N1CCOCC1

InChI Key InChIKey=NTBYWZQSJLIBPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333820   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50333820(3-(6-Morpholino-2-(2-(pyridin-2-yl)ethylamino)pyri...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant PI3K p110beta after 1 hr by radiometric scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50333820(3-(6-Morpholino-2-(2-(pyridin-2-yl)ethylamino)pyri...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant PI3K p110gamma after 1 hr by radiometric scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50333820(3-(6-Morpholino-2-(2-(pyridin-2-yl)ethylamino)pyri...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant PI3K p110alpha after 1 hr by radiometric scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed