BDBM50333817 3-(2-Morpholino-6-(2-(pyridin-2-yl)ethylamino)pyrimidin-4-yl)phenol::CHEMBL1644565

SMILES Oc1cccc(c1)-c1cc(NCCc2ccccn2)nc(n1)N1CCOCC1

InChI Key InChIKey=CXHWACFUYFVHNL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333817   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50333817(3-(2-Morpholino-6-(2-(pyridin-2-yl)ethylamino)pyri...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant PI3K p110beta after 1 hr by radiometric scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50333817(3-(2-Morpholino-6-(2-(pyridin-2-yl)ethylamino)pyri...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant PI3K p110gamma after 1 hr by radiometric scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50333817(3-(2-Morpholino-6-(2-(pyridin-2-yl)ethylamino)pyri...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant PI3K p110alpha after 1 hr by radiometric scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed