BDBM50333742 CHEMBL1643997::methyl 3-(4-((2H-tetrazol-5-yl)methyl)phenyl)-5,7-dimethylbenzo[b]thiophene-2-carboxylate

SMILES COC(=O)c1sc2c(C)cc(C)cc2c1-c1ccc(Cc2nnn[nH]2)cc1

InChI Key InChIKey=FQIHMSNTPCUEJK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333742   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333742(methyl 3-(4-((2H-tetrazol-5-yl)methyl)phenyl)-5,7-...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333742(methyl 3-(4-((2H-tetrazol-5-yl)methyl)phenyl)-5,7-...)
Affinity DataKi:  632nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333742(methyl 3-(4-((2H-tetrazol-5-yl)methyl)phenyl)-5,7-...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed