BDBM50333738 CHEMBL1644017::N,N,5,7-tetramethyl-3-(4-(2-(2-(pyridin-2-yl)acetamido)ethyl)phenyl)benzo[b]thiophene-2-carboxamide

SMILES CN(C)C(=O)c1sc2c(C)cc(C)cc2c1-c1ccc(CCNC(=O)Cc2ccccn2)cc1

InChI Key InChIKey=LSNPUSKSGBZRJH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333738   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333738(N,N,5,7-tetramethyl-3-(4-(2-(2-(pyridin-2-yl)aceta...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333738(N,N,5,7-tetramethyl-3-(4-(2-(2-(pyridin-2-yl)aceta...)
Affinity DataKi:  17nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333738(N,N,5,7-tetramethyl-3-(4-(2-(2-(pyridin-2-yl)aceta...)
Affinity DataKi:  40nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed