BDBM50333735 CHEMBL1644014::N,N,4,7-tetramethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)benzo[b]thiophene-2-carboxamide

SMILES CN(C)C(=O)c1sc2c(C)ccc(C)c2c1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

InChI Key InChIKey=WFKRGDPJQBYBAD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333735   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333735(N,N,4,7-tetramethyl-3-(4-(2-(3-tosylureido)ethyl)p...)
Affinity DataKi:  0.770nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333735(N,N,4,7-tetramethyl-3-(4-(2-(3-tosylureido)ethyl)p...)
Affinity DataKi:  19nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333735(N,N,4,7-tetramethyl-3-(4-(2-(3-tosylureido)ethyl)p...)
Affinity DataKi:  25nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed